The end of my freshman year, I had a 1.81 GPA. I applied MD with a 3.50 after averaging a 3.93 for four years (5 years to graduate), got accepted. At each interview, I heard quite the opposite - that my first year was 'understandable', but my trend afterwards was great. I even spoke with an admissions committee member at a nearby school, and he said he wouldn't even flinch at my first year. Some interviewees simply said "MCAT is great, grades are stellar" and moved on with the interview. Seriously, don't doubt the upward trend.