The example about expecting your husband home at a certain time and then not getting there until later (with you completely in the dark about it), is somewhat true. It happened to me a handful of times. My husband just finished up his 3rd year rotations, and it was a busy year to say the least. BUT, it went by so quickly and there was plenty of time to have quality time together. We even got married in the middle of 3rd year! Some people said it was crazy, but it was just fine and totally worth it.
jdh71 speaks a lot of truth. I'm sure there will be times you hate med school (I know I have) and wish he would come home when he said he may.
But overall, it is very doable. We don't have any kids, so I can't help you with that aspect, but we have some close friends (he's in my husband's class) that have 3 little ones (oldest is 7, youngest is 3) and I think trying for another. She stays home with the kiddos and they all are doing great.
Here's kind of what to expect in the first 4 years:
Year 1: Lots of studying, but normal school hours. 1st summer off. He probably will do research like everyone else that summer, but he should also enjoy it (and so should you)
Year 2: First part of the year very much like year one. Tests, classroom, studying. Then they have time off from school to just study for step 1 of the boards. This was probably the most stressful time in terms of class work and studying (it was wedding planning time for us too, but luckily i had time to do most of it). But they make their own study schedule.
Year 3: Rotations. Some are great (9-5, weekends off like psych) and others have overnight shifts and 2 days off a month, OB-Gyn and Internal Med in our case. It all depends on the hospitals at which he has his rotations. Best part - 2 weeks off for winter break.
Year 4: Just starting this for us! The first part is very similar to 3rd year with sub-internships. Also some more studying for step 2 of the boards (these tests are so expensive!!). Possibility of an externship, or an away rotation for a month. But by the end, I hear it's great - a lot of relaxation between interviews for residency programs and more time than they've ever had in med school.