The OT program is on the health science campus (HSC), which is down Broad street from Main Campus (I went to Temple for undergrad but have spent time on the HSC). The HSC is in a pretty rough area, you wouldn't want to live around there. I talked to Temple's SOTA last year and they said no one lives in the immediate area and they all commute. Some people were in Fishtown, Northern Liberties, etc. or the suburbs. You would either need to drive from outside the city or take the subway from places like Fishtown or CC. You could also just live on main campus and take the subway up to the HSC. There is a lot of crime in the surrounding area but there are also a ton of students, doctors, etc. walking around. At night time, just be vigilant and try not walk alone. I wouldn't let how "bad" the area is deter you, it's just up to you whether or not you are willing to commute!