I know someone who has failed Step 2-CK three times and is currently in the process of planning for a 4th attempt. Needless to say, failing any step more than one time will hurt one's chances in obtaining the Residency in the field and institution of choice.
Your question is hard to answer b/c you're only presenting us with one aspect of your record which, presumably, is the weakest part of your application. Your situation is much better if you've passed Step 1 on the 1st attempts and got As and Bs in most/all of your M-3 Clerkships than if you had to retake Step 1 or some of the Basic Sciences or shelf exams.
Given the information you've revealed, it's very unlikely that you'll be able to land a spot in some of the more exclusive fields like: ENT, Ortho, Ophtho, Rads, Derm, Plastics, etc. Beyond that, it's hard to comment and you probably knew this anyway.
Your best bet is to contact the programs you're interested in individually and inquire about your vialbility as an applicant. This may sound arduous but, if it's done through email, it's easy as you bascially send out the same message with different names. If done over the phone, it's not that hard either, as you can speak to the person who functions as Program Coordinator. Each inquiry should take just a few minutes.
