PTT & Factor V leiden

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a functional assay of a pt with factor V Leiden, will PTT be normal, decreased or increased ?

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[TheOther]

a functional assay of a pt with factor V Leiden, will PTT be normal, decreased or increased ?

Normal. Standard coag studies don't decrease even in hypercoagulable states.

However, if activated protein C were to be added to a PTT for a patient with Factor V Leiden there would be no/little change while a normal patient would have increased PTT.

 

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[QUOTE="if activated protein C were to be added to a PTT for a patient with Factor V Leiden there would be no/little change while a normal patient would have increased PTT.[/QUOTE]

Thank you for the clear answer.