Factor V Leiden Pt Mutation Zanki

[blockrudder1]

Can someone explain this? I thought it was a G -> A mutation, but G -> Q? Thank you in advance!

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[Pinocytosis]

Point mutation from Guanine (G) to Adenine (A) causes an amino acid substitution from Arginine to Glutamine

Resistance to activated protein C due to mutated factor V as a novel cause of inherited thrombophilia - PubMed

Inherited resistance to activated protein C (APC) was recently recognized as a novel cause underlying venous thrombophilia. In most cases APC-resistance is due to a single point mutation in the factor V gene leading to a replacement of Arg506 with Gln (factor V Leiden). Amino acid substitution...

www.ncbi.nlm.nih.gov

Edit: this, in the long run, does not matter. I was in your (presumably) pre-Step 1 shoes not too long ago. Do not sweat things like this. It is not worth the stress and frustation. Zanki, while helpful, has a lot of information that is highly specific and extremely unlikely to be tested in any Qbank, let alone the real Step 1.

 

[blockrudder1]

Point mutation from Guanine (G) to Adenine (A) causes an amino acid substitution from Arginine to Glutamine

Resistance to activated protein C due to mutated factor V as a novel cause of inherited thrombophilia - PubMed

Inherited resistance to activated protein C (APC) was recently recognized as a novel cause underlying venous thrombophilia. In most cases APC-resistance is due to a single point mutation in the factor V gene leading to a replacement of Arg506 with Gln (factor V Leiden). Amino acid substitution...

www.ncbi.nlm.nih.gov

Edit: this, in the long run, does not matter. I was in your (presumably) pre-Step 1 shoes not too long ago. Do not sweat things like this. It is not worth the stress and frustation. Zanki, while helpful, has a lot of information that is highly specific and extremely unlikely to be tested in any Qbank, let alone the real Step 1.

Oh wow, base vs AA. After so many cards I think I lose my common sense.

Thank you! That advice is really reassuring.