Please help, thanks in advance guys!
1.A 71-year old woman with coronary disease and well-controled hypertension is brought to the physician 2 hours after sudden onset of weakness of her left leg.Her BP 145/85 mmHg. Neurologic exam: weakness and decreased sensation over the left lower extremity. There are no other sensory or motor deficits. Which labeled structure is site of injury?
View attachment 201250
B(incorrect)(I thought it was pure thalamus motor and sensory stroke,but wrong)
2.A 34-year-old man with a 3 month history of a progressive rash on his feet. The rash is not ithchy or painful. A photogtaph of feet is shown. HIV+. In addition to HAART, which of the following pharmacotherapy is most appropriate?
A Antibacterial(incorrect)(I thought it was Kaposi sarcoma, but no other antiviral drug can choose, so I consider bacillary angiomatosis,which also in HIV patients, so I chose A)
B Antifungal
C Antihistaminic
D Antineoplastic(is this correct answer? since Kaposi sarcoma is also a tumor. But how to distinguish Kaposi with bacillary angiomatosis,I googled the pictures of these two disease nearly look the same)
E Antiparasitic
3.Give lovastatin, this treatment would result in which adaptive responses at cellular level?
A decreased hepatic expression of LDL-cholesterol receptors
B decreased transcription of HMG-CoA reductase(incorrect)
C increased mevalonic acid degradation
D increased mevalonic acid synthesis
E increased transcription of HMG-CoA reductase
4.A 68-year-old man with a 10-month history of shortness of breath and sweeling of his feet, family history of cardiovascular disease. He smoked 2 packs of cigarettes daily for 50 years. Puse 80/min, respirations 24/min, BP 150/80 mmHg. PE: 3+pitting edema of lower extremities. Diffuse, scattered wheezes are heard bilaterally on auscultation of the chest. Grade 2/6 pansystolic mumur heard best at lower left sternal border, which increases on inspiration. Maximal impulse palpated in sub-xiphoid area. S1 and S2 sounds are distant. Liver span 14cm. Diagnosis?
A Aortic stenosis
B Cardiac amyloidosis(incorrect)
C Cor pulmonale
D Coronary artery disease
E Primary pulmonary hypertension
Not have a clue, especially about the last 2 questions. Would anyone please give an explantion for me? Thanks a lot!