Erie has PBL which requires far less attendance and a ton of self-directed study. Erie has core sites and a (low quality but at least extant) teaching hospital that a subset of students are placed at. Other core sites usually have 1 or more residency affiliated with them. LECOM sets up almost all of your 3rd year rotations for you, and some of your 4th year. It is a good mix of self-scheduling as far as logistics/work goes (above the average for DO schools from everything I have heard and read), but really pretty frustrating with regards to lack of support and flexibility for scheduling away rotations. It is false that they make you set most rotation stuff up yourself.
LECOM students have had better match and/or placement rates than NOVA students in the recent past. LECOM students are sometimes well regarded by regional residenices (surprising to me) in non-competitive specialties. I suspect there is less of an insane competition for regional residency spots and rotations sites in this region as compared to South Florida. What I am getting at is that outcomes are better at LECOM than at NOVA and you have a better safety net for residency, because there are many regional residencies in non-competitive specialties. That is worth quite a bit of potential additional suffering in my opinion.
South Florida has sun and beaches and warmth (all of which are preferable to Erie) but it is also expensive and has potentially lower health literacy than Erie, which is A) remarkable and B) a huge drawback. Florida is also in a political climate that is potentially more polarizing than PA. Erie does have skiing nearby (low quality... but present) and is equidistant from several cities that are worth visiting at least once. It has a great state park on the lake as well. It is getting a climbing gym. I do not like Erie but I am not at all convinced that South Florida is any less of a hellscape for some people.
Given better outcomes and likely savings of 80K+, if one is neutral about the locations, or at least can find time away from the sun tolerable, LECOM is an obvious choice. I wouldn't recommend attending a DO program unless one is interested in FM, community IM, or peds.