Carbonic anhydrase Inhibitors

[zongsheng0621]

Excuse me, I'm not English native speaker
Maybe there's some expression problem

I really don't understand this

Carbonic anhydrase converts CO2 and H2O into H2CO3
and H2CO3 will become H+ and HCO3-

H+ and HCO3 transport into tubular

NaHCO3 expel

So how about H+

If H+ expel either, why is there metabolic acidosis

Why does we get hyperchloremia

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