Hey, I'm a Yale undergrad, and I've seen some post-baccers in my classes, so I can give you a little bit of information. Like you said, it's not a SMP like at Georgetown or BU. You probably get some freedom in picking what classes you take. Your advisers will probably be the same person that the Yale undergrads get, who are Ed Miller or Betsy Talcott at the Undergraduate Career Services pre-med advising panel. Ed is more experienced, and knowledgeable. I will warn you, though, that you have to put in the effort to see HIM - he's far too busy with undergrads and post-grads to come looking for you. His secretary, Bonnie, is sweet in a no-nonsense type of way, and very helpful. Make appiontments to see him early on, if you need advice. Come October, when most med apps are due, or the end of the year, when he's preparing the junior class for applying to med schools, he gets to be hard to reach.
I don't know how your grades will be calculated; I assume you'll be competing with the undergrads and just getting their grades on their same curve. In that case, it's not that hard to get a B. To get an A, however, def takes some more effort, as there are a good number of competitive undergrads at Yale. Biochemistry takes some effort, genetics is not so bad (the first test tends to get you the highest grade, so don't inflate your sense of competence in the class too early on), reproductive biology was a popular one, Orgo I and II will require a lot of effort and frustration, Physics is not so bad but don't expect the labs to work EVER, cell bio I thought was a pain in the ass but the professor is renowned so maybe getting to know him would be good for your LoRs, and inorganic was fairly easy. Yale has a lot of great electives, too, so if you have time, check them out. I recommend the History of Medicine dept if you're into that kind of stuff; there's also a survey bioethics course offered under Poli Sci.
Good luck to you!
