World question about ABO blood groups

[PayingMyDues]

I had a question about problems in pregnancy if the mother was O and the father was AB...and the answer said that it was not an issue because AB's to ABO antigens are IgM and they dont cross the placenta...however I have seen that AB's to ABO antigens can be IgG and cause HDN....any ideas???

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[Integra96]

IgG and IgM are antibodies, not RBC surface antigens. Does that clear it up at all? Sorry, I don't know what you're asking exactly.

 

[PayingMyDues]

Sorry...

What the answer states is that AB's to ABO antigens do not cross the placenta because they are IgM....however I have seen that the AB's can be either IgM or IgG...which would cross and cause a problem...