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Since this got necrobumped...for those starting from page one like me: OP's wife started an off-cycle family medicine intern year this January after receiving an offer outside the match.
Glad it worked out. Surprised she didn't wait to see whether she could get what she had dreamed of, but it wouldn't be without taking a risk. Ultimately, matching IM is also not the same as getting an oncology fellowship, so she could have matched and gone through 3 years of it only to end up doing general medicine. Being out 6 months early and only having 1-2 months break also probably kept her from getting rusty.
Also, it may not be the same, but she could deal with a similar patient population if she wished to go into Palliative medicine. I suppose it really depends on which aspects she was interested in. Not for me, but then again I wouldn't want to go into oncology either.