Trial comparing TACE to systemic chemo

[davidjones]

http://www.asco.org/ASCOv2/Meetings/Abstracts?&vmview=abst_detail_view&confID=115&abstractID=88405

Summary: Conclusions: D increased the 30-Months MS difference of 20% compared to CT. D improved responses, Performance Status and reduced costs. D reported higher immediate toxicity, mainly fever and abdominal pain, than CT. Late toxicity, mainly haematological, diarrhoea, asthenia and alopecia, was more common in CT. We conclude that D compared to CT increases survival and palliative results in patients with LM from CRC.

Plus it's over 3x cheaper

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[Gvataken]

This is very interesting. Curious what the systemic agents were. Was it folfox/folfiri/avastin etc?

This could truly change the way we treat this large population.

 

[davidjones]

FOLFIRI= folate, irinocetan and. 5FU, sometimes used with cetuximab

 

[davidjones]

Also it's much more convenient for the patient with only an average of 2 treatments for TACE vs an average of 7 for chemo