Personalised vs EBM

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Raygun77

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Just wondering on what you think the future of oncology- specifically rad onc treatment regimens- will be based on.

From an outside perspective, it seems like Rad Onc is a field heavy in evidence-based practice. I like that- but since most of the evidence is based of a TNM staging system, how good is it really for tailoring treatments? How much clinical judgement goes into modifying individual patient treatment- I'd imagine a lot. I guess i've always been a critical of the TNM system.

I like how oncology is moving towards a more cytogenetic manner of staging- do you see this reflected in more updated treatment protocol?
And do you think the day will arrive when somatic mutation profiles will guide treatment, not simply the anatomic spread of disease? It'd take a whole lot of work to replace all the current literature, that's for sure.

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