From a question in EK Bio 1001, here's an explanation to an answer:
According to the passage, osteclasts seal onto bone and release acids. The correct answer choice must be D. Osteoclasts have carbonic anhydrase that catalyzes the following reaction:
CO2 + H2O --> H2CO3 --> HCO3- + H+
Later the proton pump releases H+, with CL following, into the Howship's lacuna, which causes bone resorption.
So ultimately, osteoclasts cause bone resorption? I always thought the point of osteoclasts were to break down bone, not reabsorb it. What's going on here?
According to the passage, osteclasts seal onto bone and release acids. The correct answer choice must be D. Osteoclasts have carbonic anhydrase that catalyzes the following reaction:
CO2 + H2O --> H2CO3 --> HCO3- + H+
Later the proton pump releases H+, with CL following, into the Howship's lacuna, which causes bone resorption.
So ultimately, osteoclasts cause bone resorption? I always thought the point of osteoclasts were to break down bone, not reabsorb it. What's going on here?