QUESTION
What would be the approximate ratio of lactate to lactic acid in the final Lactated Ringer's solution after the initial preparation by student A?
(Relevant passage information: pH of solution = 6.6, Kb lactate = 2.5 x 10^-11)
a. 1:10
b. 1:1000
c. 100:1
d. 1000:1 <---correct answer
MY WORK
Ka x Kb = 1 x 10^-14 ---> Ka = (1 x 10^-14)/(2.5 x 10^-11) = 4 x 10^-4
pka = -logKa = -log (4 x 10^-4) ~ 3.4
...and then I blanked and continue to blank a day later. Anyone able to help me figure out where I go from here? The explanation at this point says:
"Solving for the ratio of [A-]/[HA] gives: lactate/lactic acid = 106.6/103.6 = 106.6 - 3.6 [my rounding of the pKa at 3.4 was a little off from there's] = 103 = 1000/1"
I'm just really uncertain of where the 106.6 and 103.6 are coming from. There is a table noting the concentration of lactate is 28 mM, but I'm not sure if that's relevant.
What would be the approximate ratio of lactate to lactic acid in the final Lactated Ringer's solution after the initial preparation by student A?
(Relevant passage information: pH of solution = 6.6, Kb lactate = 2.5 x 10^-11)
a. 1:10
b. 1:1000
c. 100:1
d. 1000:1 <---correct answer
MY WORK
Ka x Kb = 1 x 10^-14 ---> Ka = (1 x 10^-14)/(2.5 x 10^-11) = 4 x 10^-4
pka = -logKa = -log (4 x 10^-4) ~ 3.4
...and then I blanked and continue to blank a day later. Anyone able to help me figure out where I go from here? The explanation at this point says:
"Solving for the ratio of [A-]/[HA] gives: lactate/lactic acid = 106.6/103.6 = 106.6 - 3.6 [my rounding of the pKa at 3.4 was a little off from there's] = 103 = 1000/1"
I'm just really uncertain of where the 106.6 and 103.6 are coming from. There is a table noting the concentration of lactate is 28 mM, but I'm not sure if that's relevant.