Nexletol use

[bedrock]

How often do you all use Nexletol or Nexlizet in your practice?

Is it just patients with familial hypercholesterolemia or do you use it with some regularity for patients who can't lower their LDL sufficiently with a statin?

This is not a personal medical question, but I am trying to get an idea of how often these drugs are used in contemporary primary care settings

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[VA Hopeful Dr]

I have never once written for that.

Statin first, then ezetimibe, then repatha/praluent.

 

[bedrock]

I have never once written for that.

Statin first, then ezetimibe, then repatha/praluent.

Thanks for your thoughts.

How about for a patient maxed out on statins who also refuses injections?

Or for a patient with statin myopathy? (Because bempedoic acid is converted to active form in the liver not muscles, which occurs with statins).

 

[VA Hopeful Dr]

Thanks for your thoughts.

How about for a patient maxed out on statins who also refuses injections?

Assuming no ezetimibe, than enjoy your MI.

 

[bedrock]

Assuming no ezetimibe, than enjoy your MI.

Lol. I do appreciate understanding what patients would hear in the office of their PCP regarding the stepwise progression in therapy.

Though Nexlixet might be an option for such patients who refuse injectables. It’s a combo of Bempedoic acid + ezetimibe.

 

[VA Hopeful Dr]

Lol. I do appreciate understanding what patients would hear in the office of their PCP regarding the stepwise progression in therapy.

Though Nexlixet might be an option for such patients who refuse injectables. It’s a combo of Bempedoic acid + ezetimibe.

Before this thread I had literally never heard of this medication. I'll ask around at the office tomorrow and see if anyone has heard of it/uses is, but I've got my doubts.

Make of that what you will.

 

[smq123]

How often do you all use Nexletol or Nexlizet in your practice?

Is it just patients with familial hypercholesterolemia or do you use it with some regularity for patients who can't lower their LDL sufficiently with a statin?

This is not a personal medical question, but I am trying to get an idea of how often these drugs are used in contemporary primary care settings

I haven't even seen the cardiologists at my institution writing for it....

I definitely don't.

 

[smq123]

Also, this is cross posted in the cardiology subforum.

Closing.