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- Apr 6, 2015
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Hi guys, I totally bombed NBME 4. I only found threads that either discuss the scoring or that have an answer without explanations. I didn't find a thread that discusses the answers. So here goes: I have a lot of questions and I know its a lot to ask and I would be grateful for any help. I feel so depressed. I failed with a 206 (350) even after doing uworld twice with 73% the second time. Please help me!
1. 46 yo F, difficulty sleeping for 2 months. She worries about work causing her to wake up at 3 AM despite being tired. Has a hx of unstable angina requiring stent placement in the coronary artery twice. Has had chest pain that occurs daily since onset 1 mo ago. No organic cause has been found for the chest pain. She admits to being stress at work where she is an attorney. She has more responsibities now and doesn't enjoy work like she used to and reports difficulty paying attention. She is also a gourmet cook, but doesn't enjoy cooking like she used to because it doesn't taste good to her. Physical exam is normal. On mental status exam she is oriented to time, place, and person and appears anxious with a reactive affect. She admits she feels despondent a lot of the time, particularly when she thinks about her heart disease. Diagnosis?
a. Adjustment disorder (INCORRECT)
b. Dysthymic disorder
c. Generalized Anxiety disorder
d. Major depressive disorder
e. Primary Insomnia
2. 25 yo F, prenatal exam at 12 weeks gestation. She has been taking haloperidol for schizoaffective disorder until 2 mo ago. She believes the baby is evil and hears voices telling her to get an abortion. Uterus is consistent with a 12 week gestation on exam. Mental status exam shows an agitated woman. You decide to admit the patient. What additional intervention is the most appropriate next step in management?
a. Defer the decision about abortion and observe the patient. (INCORRECT)
b.Defer the decision about abortion and start valproic acid
c. Defer the decision about abortion and resume haloperidol
d. Arrange for abortion and begin valproic acid
e. Arrange for abortion and resume haloperidol
f. Arrange for the abortion and haloperidol after the abortion
3. 19 yo F, primigravid at 40 weeks gestation and uncomplicated pregnancy so far. Fetal heart monitor shows a baseline of 140/min with good variability. In 3o min her rate increases to 160/min for 25 to 30 sec. Next step in management?
a. Reassurance
b. Biophysical profile
c. Oxytocin challenge test
d. Induction of labor (INCORRECT)
e. C-section
4. 52 yo M, 30 lb weight loss over in 6 mo, oily, floating stools since 2 mo, diagnosed with acute pancreatitis 2 yrs ago with 1-3 episodes of severe abdominal pain since then. Patient takes oxycodone. Fx: mother has DM2, father died of alcoholic cirrhosis. Patient is an alcoholic but has been sober for past 2 years. He has a smoking history with 1 pack/daily for 30 yrs. BMI is 30. Vitals are normal. Abdomen in scaphoid with diffuse mild tenderness. Liver edge is firm and is palpated 2 cm below coastal margin. There are a bunch of lab values. I'll just mention a few of them: MCV 83, leukocytes 10,300, Na+ 139, K+ 3.5, HCO3 19, Glucose 164, ALP 120, AST 23, ALT 29, Amylase 90, Ferritin 250, Lipase 43 (N: 14-280). Next step in managment?
a. Dietary supplementation with a multivitamin with iron (INCORRECT)
b. Gluten free diet
c. Insulin therapy
d. Pancreatic enzyme replacement the
e. Parenteral nutrition
5. 16 yo F, yr hx of heavy bleeding with menses. Has never had spontaneous bleeding but has hx of excessive bleeding following dental procedure. Fx; father has hx of post op bleeding and nose bleeds; no bleeding disorder in mother, sister, and brother. Exam shows pallor. Labs: Hb 8, Hct 25%,, leukocyte 7000, Reticulocyte 2%, platelets 200,000, Bleeding time: 12 min, PT 13 sec with INR=1, PTT 60 sec. No abnormalities on Pelvic U/S. Mechanism of patient's bleeding?
a. Abnormal structure of Von Willebrand factor
b. Autoimmune platelet destruction
c. Bone marrow failure
d. capillary fragility
e. delay in megakaryocyte maturation
f. inadequete platelet production of prostacylin
g. inadequete production of factor VIII (INCORRECT)
6. 10 yo M with 7 day rash on arms and legs with BP 150/90. Rash is yellow, crusted, and excoriated over upper and lower extremities. Urine has 3+ protein, 30-50 RBC, 5-10 WBC. Diagnosis?
a. Acute Glomerulonephritis
b. Henoch Shonlein purpura (INCORRECT)
c. Lupus nephritis
d. Nephrolithiasis
e. Renal Neoplasm
f. UTI
7. 10 mo infant, 1 hr of labored breathing. For a duration of 18 hours has had fever, cough, coryzia. O2 saturation of 92% with bilateral crackles and wheezes. Vitals: HR 120/min, RR 54/min, BP 82/60, temp 102.2 F. Most likely pathophysiology?
a. Allergen induced bronchospasm (INCORRECT)
b. Barotrauma related alveolar disease
c. cardiac induced pulm edema
d. chemical irritant pneumonitis
e. Community acquired viral disease
f. contiguously spread bacterial infection
g. osmotically generated fluid shift
h. toxin mediated capillary leak
8. 82 yo F, hx of progressive urinary incontinence. Has strong urge to urinate at least 1x daily but is not able to reach bathroom on time, at which time she passes a large volume of urine. Other hx: arthritis of hips and knees that limits her mobility, cerebral infarction 2 yrs ago without residual weakness. Takes aspirin & lovastatin. Pelvic exam is normal. Cause of patient's incontinence?
a. Detrusor hyperactivity
b. Intrinsic weakness of urinary sphinter (INCORRECT)
c. outflow obstruction
d. poor pelvic support
e. UMN disease
9. 37 yo F, 3 mo of pain and masses in both breasts. Similar episodes that were not as severe have been occurring since 12 yrs. Use of OCPs for 16 yrs. Masses vary with menstrual cycles. Multinodular masses on exam. No adenopathy in axilla. Diagnosis?
a. benign cyst
b. breast abscess
c. breast carcinoma
d. breast engorgement
e. Ductal papilloma
f. fibroadenoma (INCORRECT)
g. Fibrocystic changes in breast
h. Mastitis
i. OCP induced breast changes
10. 32 yo G2P1 at 40 weeks, with confusion for 45 min. Has received all prenatal care from alternative provider, and has been in labor since past 3 days. Caregiver gave patient a natural product to chew this morning. resulting in strong, regular contractions. 6 hrs following this she lost conciousness suddenly. She is obtunded on arrival; vitals: 60 mmhg systolic, HR 140/min. She has a distended abdomen with rigidity. RUQ shows an irregular mobile mass that is 25 cm. Cervix is 50% effaced and 3 cm dilated with no fetal parts palpable. Cause of findings?
a. coagulopathy
b. endomyometritis
c. methamphetamine use (INCORRECT)
d. uterine atony
e. uterine rupture
11. 3 mo infant, 10 days of tacypnea and tachycardia with poor feeding. CXR: increased pulm markings & cardiomegaly, ECHO: VSD. Auscultation: 3/6 holosystolic murmur & 2/6 apical mid diastolic murmur. cause of findings?
a. excessive pulmonary blood flow
b. mitral v. obstruction
c. decreased LV contractility
d. decreased RV preload
e. RV pressure overload (INCORRECT)
12. 24 yo M, MVA with head trauma arrives comatose. He is intubated and mechanically ventilated. Vitals: HR 52/min, BP 160/94, temp 96 F. Roving eye movements. Corneal & pupillary reflexes normal. Spontaneous extention of legs and flexion of arms. DTRs are 3+ bilaterally. He is given 80 mL of 0.45% saline & urine output of 900 mL. Babinski +ve bilaterally. Labs: Na+ 147, Glucose 124, osmolality 294, urine specific gravity 1.001. CT scan: subarachnoid hemorrage & contusions. Cause of increased urine output?
a. diabetes insipidus
b. hypernatremia
c. SIADH
d. traumatic nephropathy (INCORRECT)
e. DM2
1. 46 yo F, difficulty sleeping for 2 months. She worries about work causing her to wake up at 3 AM despite being tired. Has a hx of unstable angina requiring stent placement in the coronary artery twice. Has had chest pain that occurs daily since onset 1 mo ago. No organic cause has been found for the chest pain. She admits to being stress at work where she is an attorney. She has more responsibities now and doesn't enjoy work like she used to and reports difficulty paying attention. She is also a gourmet cook, but doesn't enjoy cooking like she used to because it doesn't taste good to her. Physical exam is normal. On mental status exam she is oriented to time, place, and person and appears anxious with a reactive affect. She admits she feels despondent a lot of the time, particularly when she thinks about her heart disease. Diagnosis?
a. Adjustment disorder (INCORRECT)
b. Dysthymic disorder
c. Generalized Anxiety disorder
d. Major depressive disorder
e. Primary Insomnia
2. 25 yo F, prenatal exam at 12 weeks gestation. She has been taking haloperidol for schizoaffective disorder until 2 mo ago. She believes the baby is evil and hears voices telling her to get an abortion. Uterus is consistent with a 12 week gestation on exam. Mental status exam shows an agitated woman. You decide to admit the patient. What additional intervention is the most appropriate next step in management?
a. Defer the decision about abortion and observe the patient. (INCORRECT)
b.Defer the decision about abortion and start valproic acid
c. Defer the decision about abortion and resume haloperidol
d. Arrange for abortion and begin valproic acid
e. Arrange for abortion and resume haloperidol
f. Arrange for the abortion and haloperidol after the abortion
3. 19 yo F, primigravid at 40 weeks gestation and uncomplicated pregnancy so far. Fetal heart monitor shows a baseline of 140/min with good variability. In 3o min her rate increases to 160/min for 25 to 30 sec. Next step in management?
a. Reassurance
b. Biophysical profile
c. Oxytocin challenge test
d. Induction of labor (INCORRECT)
e. C-section
4. 52 yo M, 30 lb weight loss over in 6 mo, oily, floating stools since 2 mo, diagnosed with acute pancreatitis 2 yrs ago with 1-3 episodes of severe abdominal pain since then. Patient takes oxycodone. Fx: mother has DM2, father died of alcoholic cirrhosis. Patient is an alcoholic but has been sober for past 2 years. He has a smoking history with 1 pack/daily for 30 yrs. BMI is 30. Vitals are normal. Abdomen in scaphoid with diffuse mild tenderness. Liver edge is firm and is palpated 2 cm below coastal margin. There are a bunch of lab values. I'll just mention a few of them: MCV 83, leukocytes 10,300, Na+ 139, K+ 3.5, HCO3 19, Glucose 164, ALP 120, AST 23, ALT 29, Amylase 90, Ferritin 250, Lipase 43 (N: 14-280). Next step in managment?
a. Dietary supplementation with a multivitamin with iron (INCORRECT)
b. Gluten free diet
c. Insulin therapy
d. Pancreatic enzyme replacement the
e. Parenteral nutrition
5. 16 yo F, yr hx of heavy bleeding with menses. Has never had spontaneous bleeding but has hx of excessive bleeding following dental procedure. Fx; father has hx of post op bleeding and nose bleeds; no bleeding disorder in mother, sister, and brother. Exam shows pallor. Labs: Hb 8, Hct 25%,, leukocyte 7000, Reticulocyte 2%, platelets 200,000, Bleeding time: 12 min, PT 13 sec with INR=1, PTT 60 sec. No abnormalities on Pelvic U/S. Mechanism of patient's bleeding?
a. Abnormal structure of Von Willebrand factor
b. Autoimmune platelet destruction
c. Bone marrow failure
d. capillary fragility
e. delay in megakaryocyte maturation
f. inadequete platelet production of prostacylin
g. inadequete production of factor VIII (INCORRECT)
6. 10 yo M with 7 day rash on arms and legs with BP 150/90. Rash is yellow, crusted, and excoriated over upper and lower extremities. Urine has 3+ protein, 30-50 RBC, 5-10 WBC. Diagnosis?
a. Acute Glomerulonephritis
b. Henoch Shonlein purpura (INCORRECT)
c. Lupus nephritis
d. Nephrolithiasis
e. Renal Neoplasm
f. UTI
7. 10 mo infant, 1 hr of labored breathing. For a duration of 18 hours has had fever, cough, coryzia. O2 saturation of 92% with bilateral crackles and wheezes. Vitals: HR 120/min, RR 54/min, BP 82/60, temp 102.2 F. Most likely pathophysiology?
a. Allergen induced bronchospasm (INCORRECT)
b. Barotrauma related alveolar disease
c. cardiac induced pulm edema
d. chemical irritant pneumonitis
e. Community acquired viral disease
f. contiguously spread bacterial infection
g. osmotically generated fluid shift
h. toxin mediated capillary leak
8. 82 yo F, hx of progressive urinary incontinence. Has strong urge to urinate at least 1x daily but is not able to reach bathroom on time, at which time she passes a large volume of urine. Other hx: arthritis of hips and knees that limits her mobility, cerebral infarction 2 yrs ago without residual weakness. Takes aspirin & lovastatin. Pelvic exam is normal. Cause of patient's incontinence?
a. Detrusor hyperactivity
b. Intrinsic weakness of urinary sphinter (INCORRECT)
c. outflow obstruction
d. poor pelvic support
e. UMN disease
9. 37 yo F, 3 mo of pain and masses in both breasts. Similar episodes that were not as severe have been occurring since 12 yrs. Use of OCPs for 16 yrs. Masses vary with menstrual cycles. Multinodular masses on exam. No adenopathy in axilla. Diagnosis?
a. benign cyst
b. breast abscess
c. breast carcinoma
d. breast engorgement
e. Ductal papilloma
f. fibroadenoma (INCORRECT)
g. Fibrocystic changes in breast
h. Mastitis
i. OCP induced breast changes
10. 32 yo G2P1 at 40 weeks, with confusion for 45 min. Has received all prenatal care from alternative provider, and has been in labor since past 3 days. Caregiver gave patient a natural product to chew this morning. resulting in strong, regular contractions. 6 hrs following this she lost conciousness suddenly. She is obtunded on arrival; vitals: 60 mmhg systolic, HR 140/min. She has a distended abdomen with rigidity. RUQ shows an irregular mobile mass that is 25 cm. Cervix is 50% effaced and 3 cm dilated with no fetal parts palpable. Cause of findings?
a. coagulopathy
b. endomyometritis
c. methamphetamine use (INCORRECT)
d. uterine atony
e. uterine rupture
11. 3 mo infant, 10 days of tacypnea and tachycardia with poor feeding. CXR: increased pulm markings & cardiomegaly, ECHO: VSD. Auscultation: 3/6 holosystolic murmur & 2/6 apical mid diastolic murmur. cause of findings?
a. excessive pulmonary blood flow
b. mitral v. obstruction
c. decreased LV contractility
d. decreased RV preload
e. RV pressure overload (INCORRECT)
12. 24 yo M, MVA with head trauma arrives comatose. He is intubated and mechanically ventilated. Vitals: HR 52/min, BP 160/94, temp 96 F. Roving eye movements. Corneal & pupillary reflexes normal. Spontaneous extention of legs and flexion of arms. DTRs are 3+ bilaterally. He is given 80 mL of 0.45% saline & urine output of 900 mL. Babinski +ve bilaterally. Labs: Na+ 147, Glucose 124, osmolality 294, urine specific gravity 1.001. CT scan: subarachnoid hemorrage & contusions. Cause of increased urine output?
a. diabetes insipidus
b. hypernatremia
c. SIADH
d. traumatic nephropathy (INCORRECT)
e. DM2