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Isn't breast milk also deficient in certain vitamins (D maybe?) that preemies aren't able to metabolize yet? I remember hearing something to that effect, but that was a long time ago.
ShyRem said:Centigrade, Fahrenheit, or Kelvin? Isn't zero K a hypothetical and can't be measured?
toofache32 said:My favorites:
"Describe the pathophysiology of anemia of chronic disease. Be brief."
"Which state is the shape of a perfect square?"
What about aminophylline?oldbearprofessor said:Doxapram has been tried without much success. Caffeine is both safe and effective.
Regards
OBP
DropkickMurphy said:What about aminophylline?
Duly noted.....seeing as I've never worked NICU, that would explain why I'm not up to speed on neonatology. Thanks for the clarification.oldbearprofessor said:The drug of choice in the 1980's! Worked well, but we needed to monitor levels carefully.
Caffeine has the same effect with a greater safety margin - less tachycardia.
Also, breast milk is low in vitamin D - that's why all breast fed babies, preterm or fullterm get supplemental vitamin D. Initially, the metabolism (i.e. conversion to the active form) is minimal in preterms but then it increases after a couple of weeks.
However, that isn't really why we use human milk fortifier.
etf said:wasn't this the interview question in harold and kumar? or was it about the symptoms?
Purifyer said:With the neurocutaneous syndromes he wanted me to list them, whether autosomal dominant/not and the typical phenotypic effects. One thing I learnt from this pimping was that there are ALOT more neurocutaneous syndromes than just NF1 NF2 Tuberous sclerosis, Sturge-Weber, ataxia-telangiectasia and VHL.
Purifyer said:Nice Bill
with the 'mesial' hippocampal sclerosis the actual question went something along the lines of 'someone with epilepsy - scans normal... what are you thinking/next step in management? (after he had rejected every epiltogenic scenario I could conjure)' [me: idiopathic? 'NO' psychogenic 'NO' ],It was so far over my head I can't even remember the question properly but essentially he wanted 'measure the volume of the hippocampi on MRI' or something similar, with one hippocampus being smaller than the contralateral one.
I said yes to the radiosurgery one as well but he wanted a 'no'. Depends on the definition of 'effective' - radiosurgery does decrease risk of haemorrhage from cavernomas but doesn't cause involution/reduction in size.
Diffusely inverted T waves - SAH neurocardiogenic effects, acute coronary syndromes... my registrar (resident) also mentioned hypokalaemia but I doubt that's correct.
With the neurocutaneous syndromes he wanted me to list them, whether autosomal dominant/not and the typical phenotypic effects. One thing I learnt from this pimping was that there are ALOT more neurocutaneous syndromes than just NF1 NF2 Tuberous sclerosis, Sturge-Weber, ataxia-telangiectasia and VHL.
Another random fact - SAH can cause fever (obvious I suppose).
jojo14 said:What is the most common EKG finding in pulmonary embolism?
beastmaster said:1) What happens when you answer a pimp question correctly ?
2) What happens when you don't ?
GuP said:b - "Which state is the shape of a perfect square?"
b - I guess a perfect square is in a state of total harmony and equilibrium? (no idea)
close enoughyobynaes said:Colorado ?
Purifyer said:Nice Bill
Diffusely inverted T waves - SAH neurocardiogenic effects, acute coronary syndromes... my registrar (resident) also mentioned hypokalaemia but I doubt that's correct. QUOTE]
HypoK can flip your Ts, as can many different intracranial processes, SAH only being the most classic.
Less than 35...just because there are more of them. Right?cytoskelement said:Are more babies born with Trisomy 21 of mothers less than 35 or greater than 35?
oldbearprofessor said:The drug of choice in the 1980's! Worked well, but we needed to monitor levels carefully.
Caffeine has the same effect with a greater safety margin - less tachycardia.
Also, breast milk is low in vitamin D - that's why all breast fed babies, preterm or fullterm get supplemental vitamin D. Initially, the metabolism (i.e. conversion to the active form) is minimal in preterms but then it increases after a couple of weeks.
However, that isn't really why we use human milk fortifier.
closertofine said:Is it iron? Can't remember exactly, but something like breast milk has some iron, but it's not easily absorbed by babies?
Anasazi23 said:I still remember some psychiatry pimp questions:
3. Which antibiotic is chemically closely related to an MAOI, disallowing the patient to eat foods containing tyramine?
oldbearprofessor said:Breast milk is low in iron - full-term infants don't need much in the first 6 months of life as they primarily rely on liver stores. It is well absorbed however. Preterm babies miss out on the iron storage part of in utero development so they need extra iron after birth, although for several reasons we are cautious about providing too much too soon. Of the two available commercial human milk fortifiers, one has extra iron the other doesn't (for babies who get that fortifier, iron drops are used).
But that isn't the main reason for fortifying mother's milk for premature babies.
arroser said:Premed research assistant on feeding in preterms here... and I'm totally guessing.
Mother's milk has everything the babies need, but not concentrated enough? I know a lot of the subjects I work with are restricted to about 150ml/kg. Fortifying gets more nutrients for the volume?
oldbearprofessor said:Too vague an answer....what specific macro or micor nutrient(s)?
OBP
arroser said:OK, it isn't primarily calories, so I'll cross off fats. Vitamin D is wrong. So... Vitamin E, I think, is often deficient in premies. I'll go with calcium and phosphorus too, plus protein, since the babies are (hopefully!) growing.
Igor said:My favorite pimp questions, honest are:
...
Tell me 10 animals that only have 3 letters in their name
I had a student who had been a zoology major that couldn't get this one!
Shane2150 said:"Name 10 parts of the body that only have 3 letters in their name.
(Must be common, i.e. layman's, terms; all are G-rated)"
beachbunny said:Ok, I think I got it....
ear, eye, arm, rib, gut, rib, hip, ass, leg, toe
NKMU said:Name at least five side effects of amiodarone.
-Finally, one I could do easily!
Followup question: describe in detail the mechanism of each of those side effects. Clearly I fumbled, then he rattled them off.
oldbearprofessor said:What are the MEDICAL (baby or mom) absolute or strong relative contraindications to breast-feeding or providing mother's own milk for a baby? (hint, there are very few, but some exist).
Mom: HIV infection
Active TB
CMV
Hep B/C
HTL Virus type I and II
Cytotoxic drugs
Immunosuppresive drugs
Other drugs that pass into the breast milk (high conc in milk)
medgirl20 said:oldbearprofessor said:What are the MEDICAL (baby or mom) absolute or strong relative contraindications to breast-feeding or providing mother's own milk for a baby? (hint, there are very few, but some exist).
Mom: HIV infection
Active TB
CMV
Hep B/C
HTL Virus type I and II
Cytotoxic drugs
Immunosuppresive drugs
Other drugs that pass into the breast milk (high conc in milk)
http://www.cdc.gov/cmv/facts.htm
50-80% of adults in the US are CMV positive. It would be a challenge to meet the goal of 80% breast-feeding if we eliminated these moms from breastfeeding.
Hepatitis C may not be an issue either. http://www.medicalnewstoday.com/medicalnews.php?newsid=32915
Almost all "drugs" pass into human milk, most at unknown or highly variable concentrations. What defines "high" concentration? How would one decide whether to permit breast-feeding? Would it matter if the drug was a legal one???
Some of your others are reasonable. I'll let others take a shot at this before commenting further. The HIV issue is complex.
OBP
oldbearprofessor said:What are the MEDICAL (baby or mom) absolute or strong relative contraindications to breast-feeding or providing mother's own milk for a baby? (hint, there are very few, but some exist).
Among formula-fed babies, what are the indications for using special formulas such as soy, lactose-free, hypoallergenic or transitional formulas?
Baby Einstein said:Contraindications on baby's part: galactosemia + maybe structural abnormalities like cleft palate (although could get expressed breast milk).
Formulas:
- soy if baby is allergic to cow's milk proteins
- lactose free if baby is lactose intolerant (duh!)
- hypoallergenic if baby is allergic to both cow's milk and soybean (guessing)
medgirl20 said:If the drug was illegal contraindication to breast feeding
For other drugs I'd refer to my BNF