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In an aldol condensation during the dehydration part, what role does NH4Cl play?
I'm a bit confused. Thanks!!
I'm a bit confused. Thanks!!
I'm not super fresh on the Aldol Condensation, but anytime you see an ammonium salt (NH4+Cl-) you can be assured that the purpose of it is to protonate something.In an aldol condensation during the dehydration part, what role does NH4Cl play?
I'm a bit confused. Thanks!!
In an aldol condensation during the dehydration part, what role does NH4Cl play?
I'm a bit confused. Thanks!!
I want to say A....but how can you determine whether its exclusively E1 vs E2?A) It serves to protonate the OH and make it a better leaving group, so that the ß-hydroxy-ketone can undergo an E1 elimination.
B) It serves to protonate the OH and make it a better leaving group, so that the ß-hydroxy-ketone can undergo an E2 elimination.
C) It forms an imine intermediate from the ß-hydroxy-ketone, which makes OH a better leaving group.
D) It readily absorbs water, preventing hydrolysis of the conjugated ketone to form an alpha-hydroxyketone.
I want to say A....but how can you determine whether its exclusively E1 vs E2?