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Agreed with the above... I rarely will refill something relatively innocuous that they're already on such as lisinopril or albuterol and it's a weekend. But not abx, narcs, benzos, or amphetamines.
As far as the relationship question goes, the standardized tests during med school were very black-and-white about this. If you first met the person because they were your pt, you may not have an out-of-work relationship with them, ever, full-stop. I'm not such an absolutist; and I believe that setting strict emotional barriers between yourself and your patients may actually impede health care. On the other hand, boning your patients is unacceptable unless you are a U.S. congressman from Tennessee.
A point above was that if you go down the road of "out of work relationships" this sometimes could lead to the "boning", especially if alcohol and other bad judgment is involved in the encounter. Or can lead to tacit endorsement of activities (smoking, drinking, drugs, non-heart healthy diet, etc) that the patient is subconsciously relying on you to put the brakes on if you are there. You can never ethically be just a buddy and one of the guys if you also had ever been in the role of caregiver.
I agree that writing family scrips is probably not wise, particularly now days where it's trivial to just go to the NP working at CVS or Walmart who is happy to see you immediately and prescribe you things as freely as a Pez dispenser.