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What's the best way (in a patient with wheezing), to determine if this is likely due to reactive airway disease or asthma exacerbation, vs a viral illness?
Have a fancy lab with a respiratory viral panel and see if something comes up positive.
Or look for other symptoms (nasal congestion, rhinorrhea, fevers, conjunctivitis, sick contacts, etc), recognizing that some overlap with seasonal allergies, so you'll need to know if they have those and if they were exposed to any of their allergens.
Aren't rvps like $1500? Wouldn't it be better to just trial a bronchodilator?
That's a far more useful paper.
That's a far more useful paper.
I think the multiplex viral panels are useful only if they are going to change management*(cohort with other children with same disease process, forgo abx, forgo other testing to search for etiology of illness). They so sound very cool because we can say definitively "it's X" rather then "umm, probably a virus?". Ordered thoughtfully, they can be helpful.
However, I fear they will become an extension (a potentially much more expensive extension) of the RSV RADT. A test that tells you about exactly one virus and absolutely nothing about the child's hydration and respiratory status.
*Exceptions would include research and certain public health purposes.
Also, our nurses in the PICU have gotten into a habit of not putting kids in isolation unless there is an RVP ordered or a result from an OSH.
I don't need a $1000 test to tell me that someone has a virus.
Also, our nurses in the PICU have gotten into a habit of not putting kids in isolation unless there is an RVP ordered or a result from an OSH.
Generally agree with this, but I will say that in the real world there is some additional value to these tests beyond "would it change management"
Example -- parent got angry at me once because I told them their child had viral bronchiolitis. Patient got worse, went to hospital where they had a positive rapid RSV test. Parent was mad because their child had "RSV instead of a virus." Even though the management didnt change, knowing the specific virus causing the illness was highly valuable to the parent.
I would also say that these viral panels can change management in ways that you don't initially consider.
Example -- kid comes in with 6 days of fevers, weakness/fatigue, joint pains, conjunctivitis, large lymph node in neck. I'm starting to think about Kawasaki and perhaps admit them for IVIG. However I first run a viral panel which comes back positive for adenovirus. That has happened at least twice in my career, and now before I diagnose Kawasaki I always check for adeno first since it's such a great mimicker of Kawasaki
Now there are a couple of companies that can do a rapid FA6 viral panel with results in 2 hours that are much less expensive -- I saw one that costs under $30 for PPO insurance plans.