Of course I'm a rock star GI doc. Seriously, don't worry about offending me.
@pgg accused me of pearl clutching earlier ITT (had to look that up) and I still like him.
When the intent is GA, that's very different than moderate sedation. If I walk away from my patient and turn off the oxygen, he'll be fine. If you walk, my kid is dead.
Maybe I'm more comfortable than I should be. I'm only 10,000 procedures past my fellowship and sedation deaths from colonoscopy in the community are somewhere between 1:25k and 1:100k. My group does 30k+ scopes/year and have had 2 events related to ERCP sedation in the distant past. We've used reversals once this year and probably didn't need to (there was an error here, new attending who trained in a program with all CRNAs). We use capnography (although I'm not a believer since we shouldn't need it and it's one more thing to distract the nurses: you are right, there is no waveform. However that is because the patient is trying to speak, etc).
WRT your anecdotes: 32mg of versed is malpractice. 6 and 150 is also a truckload but might be ok in a looooong procedure with a benzo/opioid tolerant patient. I'm not sure what you meant about talking a patient through the procedure but we do that all the time. We know more versed won't help.
I totally agree propofol is better from a patient satisfaction perspective but there's no evidence it's safer. I saw more respiratory events and near misses in advanced fellowship with CRNAs. I think GI expectations drive that. When we are sedating, we will go light. When you are...well why are you here if the patients going to move around like they do for me.
I do lots of awake scopes on physicians, fewer on spouses. I suspect your GI knew he was taking care of an anesthesiologist' spouse and really didn't want her to remember.
We have an ongoing feud with one of our endoscopist. He owns his own shop and uses a crna for which he bills for and never meets a pt until he is about to send a camera up their ass. A PA does all the clinic work. He sends us his cases that the nurse won't do. So he uses an anesthesia professional all while claiming they bring more risk. I guess money is more important to him. He sent me these studies. I know there is a lot here. Critique as you will.
Articles (and accompanying editorials) discussing the risks of endoscopic or anesthesia-related complications associated with propofol-based sedation
Gastrointest Endosc. 2017 Jan;85(1):101-108. doi: 10.1016/j.gie.2016.02.007. Epub
2016 Feb 18.
Patient safety during sedation by anesthesia professionals during routine upper
endoscopy and colonoscopy: an analysis of 1.38 million procedures.
Vargo JJ(1), Niklewski PJ(2), Williams JL(3), Martin JF(4), Faigel DO(5).
Author information:
(1)Department of Gastroenterology and Hepatology, Digestive Disease Institute,
Cleveland Clinic, Cleveland, Ohio, USA. (2)Ethicon Endo-Surgery Inc., Cincinnati,
Ohio, USA; Department of Pharmacology and Cell Biophysics, College of Medicine,
University of Cincinnati, Cincinnati, Ohio, USA. (3)Division of Gastroenterology,
Oregon Health and Science University, Portland, Oregon, USA. (4)Ethicon
Endo-Surgery Inc., Cincinnati, Ohio, USA. (5)Division of Gastroenterology and
Hepatology, Mayo Clinic, Scottsdale, Arizona, USA.
BACKGROUND AND AIMS: Sedation for GI endoscopy directed by anesthesia
professionals (ADS) is used with the intention of improving throughput and
patient satisfaction. However, data on its safety are sparse because of the lack
of adequately powered, randomized controlled trials comparing it with
endoscopist-directed sedation (EDS). This study was intended to determine whether
ADS provides a safety advantage when compared with EDS for EGD and colonoscopy.
METHODS: This retrospective, nonrandomized, observational cohort study used the
Clinical Outcomes Research Initiative National Endoscopic Database, a network of
84 sites in the United States composed of academic, community, health maintenance
organization, military, and Veterans Affairs practices. Serious adverse events
(SAEs) were defined as any event requiring administration of cardiopulmonary
resuscitation, hospital or emergency department admission, administration of
rescue/reversal medication, emergency surgery, procedure termination because of
an adverse event, intraprocedural adverse events requiring intervention, or blood
transfusion.
RESULTS: There were 1,388,235 patients in this study that included 880,182
colonoscopy procedures (21% ADS) and 508,053 EGD procedures (23% ADS) between
2002 and 2013. When compared with EDS, the propensity-adjusted SAE risk for
patients receiving ADS was similar for colonoscopy (OR, .93; 95% CI, .82-1.06)
but higher for EGD (OR, 1.33; 95% CI, 1.18-1.50). Additionally, with further
stratification by American Society of Anesthesiologists (ASA) class, the use of
ADS was associated with a higher SAE risk for ASA I/II and ASA III subjects
undergoing EGD and showed no difference for either group undergoing colonoscopy.
The sample size was not sufficient to make a conclusion regarding ASA IV/V
patients.
CONCLUSIONS: Within the confines of the SAE definitions used, use of anesthesia
professionals does not appear to bring a safety benefit to patients receiving
colonoscopy and is associated with an increased SAE risk for ASA I, II, and III
patients undergoing EGD.
Gastrointest Endosc. 2017 Jan;85(1):109-111. doi: 10.1016/j.gie.2016.06.025.
The endoscopist, the anesthesiologists, and safety in GI endoscopy.
Repici A(1), Hassan C(2).
Author information:
(1)Endoscopy Unit, Humanitas Research Hospital, Rozzano, Milano, Italy; Humanitas
University, Milano, Italy. (2)Endoscopy Unit, Nuovo Regina Margherita Hospital,
Rome, Italy.
Gastroenterology. 2016 Apr;150(4):888-94; quiz e18. doi:
10.1053/j.gastro.2015.12.018. Epub 2015 Dec 18.
Risks Associated With Anesthesia Services During Colonoscopy.
Wernli KJ(1), Brenner AT(2), Rutter CM(3), Inadomi JM(2).
Author information:
(1)Group Health Research Institute, Seattle, Washington; Department of Health
Services, University of Washington, Seattle, Washington. Electronic address:
[email protected]. (2)Department of Health Services, University of Washington,
Seattle, Washington; Division of Gastroenterology, Department of Medicine,
University of Washington, Seattle, Washington. (3)Group Health Research
Institute, Seattle, Washington; RAND Corporation, Santa Monica, California.
Comment in
Gastroenterology. 2016 Apr;150(4):801-3.
BACKGROUND & AIMS: We aimed to quantify the difference in complications from
colonoscopy with vs without anesthesia services.
METHODS: We conducted a prospective cohort study and analyzed administrative
claims data from Truven Health Analytics MarketScan Research Databases from 2008
through 2011. We identified 3,168,228 colonoscopy procedures in men and women,
aged 40-64 years old. Colonoscopy complications were measured within 30 days,
including colonic (ie, perforation, hemorrhage, abdominal pain),
anesthesia-associated (ie, pneumonia, infection, complications secondary to
anesthesia), and cardiopulmonary outcomes (ie, hypotension, myocardial
infarction, stroke), adjusted for age, sex, polypectomy status, Charlson
comorbidity score, region, and calendar year.
RESULTS: Nationwide, 34.4% of colonoscopies were conducted with anesthesia
services. Rates of use varied significantly by region (53% in the Northeast vs 8%
in the West; P < .0001). Use of anesthesia service was associated with a 13%
increase in the risk of any complication within 30 days (95% confidence interval
[CI], 1.12-1.14), and was associated specifically with an increased risk of
perforation (odds ratio [OR], 1.07; 95% CI, 1.00-1.15), hemorrhage (OR, 1.28; 95%
CI, 1.27-1.30), abdominal pain (OR, 1.07; 95% CI, 1.05-1.08), complications
secondary to anesthesia (OR, 1.15; 95% CI, 1.05-1.28), and stroke (OR, 1.04; 95%
CI, 1.00-1.08). For most outcomes, there were no differences in risk with
anesthesia services by polypectomy status. However, the risk of perforation
associated with anesthesia services was increased only in patients with a
polypectomy (OR, 1.26; 95% CI, 1.09-1.52). In the Northeast, use of anesthesia
services was associated with a 12% increase in risk of any complication; among
colonoscopies performed in the West, use of anesthesia services was associated
with a 60% increase in risk.
CONCLUSIONS: The overall risk of complications after colonoscopy increases when
individuals receive anesthesia services. The widespread adoption of anesthesia
services with colonoscopy should be considered within the context of all
potential risks.
Gastrointest Endosc. 2014 Apr;79(4):657-62. doi: 10.1016/j.gie.2013.12.002. Epub
2014 Jan 25.
Effect of propofol anesthesia on force application during colonoscopy.
Korman LY(1), Haddad NG(2), Metz DC(3), Brandt LJ(4), Benjamin SB(2), Lazerow
SK(5), Miller HL(5), Mete M(6), Patel M(7), Egorov V(7).
Author information:
(1)Chevy Chase Clinical Research, Chevy Chase, Maryland, USA. (2)Division of
Gastroenterology, Georgetown University Hospital, Georgetown University School of
Medicine, Washington, DC, USA. (3)Division of Gastroenterology, Hospital
University of Pennsylvania, University of Pennsylvania School of Medicine,
Philadelphia, Pennsylvania, USA. (4)Division of Gastroenterology, Montefiorep
Medical Center, Albert Einstein School of Medicine, Bronx, New York, USA.
(5)Gastroenterology Division, Department of Veterans Affairs Medical Center,
Washington, DC, USA. (6)Department of Biostatistics and Bioinformatics, MedStar
Health Research Institute, Washington, DC, USA. (7)Artann Laboratories, Trenton,
New Jersey, USA.
BACKGROUND: Sedation is frequently used during colonoscopy to control patient
discomfort and pain. Propofol is associated with a deeper level of sedation than
is a combination of a narcotic and sedative hypnotic and, therefore, may be
associated with an increase in force applied to the colonoscope to advance and
withdraw the instrument.
OBJECTIVE: To compare force application to the colonoscope insertion tube during
propofol anesthesia and moderate sedation.
DESIGN: An observational cohort study of 13 expert and 12 trainee endoscopists
performing colonoscopy in 114 patients. Forces were measured by using the
colonoscopy force monitor, which is a wireless, handheld device that attaches to
the insertion tube of the colonoscope.
SETTING: Community ambulatory surgery center and academic gastroenterology
training programs.
PATIENTS: Patients undergoing routine screening or diagnostic colonoscopy with
complete segment force recordings.
MAIN OUTCOME MEASUREMENTS: Axial and radial forces and examination time.
RESULTS: Axial and radial forces increase and examination time decreases
significantly when propofol is used as the method of anesthesia.
LIMITATIONS: Small study, observational design, nonrandomized distribution of
sedation type and experience level, different instrument type and effect of
prototype device on insertion tube manipulation.
CONCLUSIONS: Propofol sedation is associated with a decrease in examination time
and an increase in axial and radial forces used to advance the colonoscope.
JAMA Intern Med. 2013 Apr 8;173(7):551-6. doi: 10.1001/jamainternmed.2013.2908.
Complications following colonoscopy with anesthesia assistance: a
population-based analysis.
Cooper GS(1), Kou TD, Rex DK.
Author information:
(1)Division of Gastroenterology, University Hospitals Case Medical Center,
Cleveland, OH 44106, USA.
[email protected]
Comment in
JAMA Intern Med. 2013 Apr 8;173(7):556-8.
JAMA Intern Med. 2013 Sep 23;173(17):1660.
JAMA Intern Med. 2013 Sep 23;173(17):1659-60.
IMPORTANCE: Deep sedation for endoscopic procedures has become an increasingly
used option but, because of impairment in patient response, this technique also
has the potential for a greater likelihood of adverse events. The incidence of
these complications has not been well studied at a population level.
DESIGN: Population-based study.
SETTING AND PARTICIPANTS: Using a 5% random sample of cancer-free Medicare
beneficiaries who resided in one of the regions served by a SEER (Surveillance,
Epidemiology, and End Results) registry, we identified all procedural claims for
outpatient colonoscopy without polypectomy from January 1, 2000, through November
30, 2009.
INTERVENTION: Colonoscopy without polypectomy, with or without the use of deep
sedation (identified by a concurrent claim for anesthesia services).
MAIN OUTCOME MEASURES: The occurrence of hospitalizations for splenic rupture or
trauma, colonic perforation, and aspiration pneumonia within 30 days of the
colonoscopy.
RESULTS: We identified a total of 165 527 procedures in 100 359 patients,
including 35 128 procedures with anesthesia services (21.2%). Selected
postprocedure complications were documented after 284 procedures (0.17%) and
included aspiration (n = 173), perforation (n = 101), and splenic injury (n =
12). (Some patients had >1 complication.) Overall complications were more common
in cases with anesthesia assistance (0.22% [95% CI, 0.18%-0.27%]) than in others
(0.16% [0.14%-0.18%]) (P < .001), as was aspiration (0.14% [0.11%-0.18%] vs 0.10%
[0.08%-0.12%], respectively; P = .02). Frequencies of perforation and splenic
injury were statistically similar. Other predictors of complications included age
greater than 70 years, increasing comorbidity, and performance of the procedure
in a hospital setting. In multivariate analysis, use of anesthesia services was
associated with an increased complication risk (odds ratio, 1.46 [95% CI,
1.09-1.94]).
CONCLUSIONS AND RELEVANCE: Although the absolute risk of complications is low,
the use of anesthesia services for colonoscopy is associated with a somewhat
higher frequency of complications, specifically, aspiration pneumonia. The
differences may result in part from uncontrolled confounding, but they may also
reflect the impairment of normal patient responses with the use of deep sedation.
JAMA Intern Med. 2013 Apr 8;173(7):556-8. doi: 10.1001/jamainternmed.2013.4071.
Anesthesia for colonoscopy: too much of a good thing?
Wernli KJ(1), Inadomi JM.
Author information:
(1)Group Health Research Institute, Seattle, WA 98195, USA.
Comment on
JAMA Intern Med. 2013 Apr 8;173(7):551-6.