Would appreciate some help and explanation of the following NBME 1 questions:
1. Parkinson's pt on carbidopa-levodopa and pramipexole with inc depressive symptoms for past 3 weeks, flat/tearful affect, doesn't want to go anywhere or do anything, says "who wouldn't be sad with this disease." What is the diagnosis?
Options: adjustment with depressed mood (not it), adverse effect of carbidopa-levodopa, dysthymic disorder, MDD, normal reaction to chronic medical illness
2. 52yo woman with weird feeling in her calves when trying to go to bed that keeps her up at night for a couple of hours and is affecting her work/causing her stress.
Options: conversion disorder, dysthymic disorder, GAD, OSA, restless leg (possibly this but no mention of legs moving uncontrollably at night), normal sleep phenomena
3. 5yo girl with difficulty learning and completing basic assignments. Happy and eager to please. Has epicanthal folds, II/VI murmur as LSB, 30th %ile for height, can't hop on one foot, and knows half of her alphabets
Options: Angelman, Down, FAS (is it this?), Fragile X, Prader-Willi, Rett
4. 25yo woman brought in after running in front of cars at busy intersection. Grandiose delusions, combative, hyperverbal. How do you treat her acute symptoms?
Options: fluoxetine, hydroxyzine, lamotrigine, lithium (not it), ziprasidone (possibly this?)
5. 42yo man who has 2mo history of 1-2 min long staring spells that are accompanied with some lip smacking and picking his shirt collar. Was in a coma 4 yrs ago after motorcycle accident. Smells burnt rubber and hears hissing sound during spells. What will the EEG look like?
Options: burst-suppression pattern, diffuse 3-hz spike and slow wave activity (not it), focal spikes localized in temporal lobe, hypsarrhythmia, periodic lateralized epileptiform discharges, polyspike and slow wave activity, triphasic waves
6. 77yo man with 6mo history of confusion and "slowing down", visual hallucinations that he talks to, fails mini-cog, has history of CABG 15 yrs ago and might have a fib (HR 102 with irregular rhythm). Has decreased muscle tone and slow, narrow-based gait. What's the diagnosis?
Options: alzheimer's, drug abuse, lewy body dementia, multi-infarct dementia (not it), tumor of parietal lobe