NMJ AChR upregulation causes

[PMPMD]

NMJ AChR upregulation causes
Nicotinic AChR upregulation:
• Spinal cord injury
• Stroke
• Burns
• Prolonged immobility
• Prolonged exposure to neuromuscular blockers
• Multiple sclerosis
• Guillain-Barre syndrome
Nicotinic AChR downregulation
• Myasthenia gravis
• Anticholinesterase poisoning
• Organophosphate poisoning
[Miller Box 29-1]

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